Endocrine Abstracts

Introduction: Langerhans cell histiocytosis (LCH) is a rare disorder with variable clinical presentations. Among the endocrine compromise, the LCH has a predilection for the hypothalamic-pituitary axis. However, primary thyroid involvement is rare and usually related to multisystemic disease.Case Report: We present a 30-year-old woman who requested a medical consultation because of polyuria and was found to have central diabetes insipidus (CDI). The pati...

Introduction: The prevalence of brain metastasis from differentiated thyroid carcinoma is 1%. Brain metastasis as the first manifestation of the disease is extremely uncommon.Case report: We present a case of 44-year-old woman with headache and a tumor in right parietal zone. The patient has had multinodular goiter for 15 years, with two dominant nodules in left thyroid lobe. Both of them were isoechoic with hypoechoic halo and measured 2 cm. Fine-needle...

Introduction: Malignancy is an uncommon cause of adrenal incidentaloma in patients without a known diagnosis of cancer. The actual frequency of primary adrenal carcinoma in patients with adrenal incidentaloma is ~2–5%; another 0.7–2.5% have nonadrenal metastases to the adrenal gland. The presence of a nonadrenal primary tumour is exceptional and has been scarcely reported in medical literature.Case report: We present a case of 71-year-old male ...

Introduction: Sclerostin, produced by osteocytes, is a potent inhibitor of Wnt signaling and bone formation. The usefulness of its determination in clinical practice is not well established.Objectives: The aims of this study were to evaluate serum sclerostin levels in a cohort of Spanish posmenopausal women, and to analyze its relationship with bone metabolism.Methods: We measured serum sclerostin in 97 posmenopausal women using EL...

Introduction: Postprandial glycemic control is complex as well as insufficient. Its impact on global metabolic control (HbA1c) is controversial with various works that support its influence in terms of glycemic variability and genesis of micro and/or macrovascular complications. Fiasp due to its special formulation allows a more effective control of postprandial glycemia being an interesting alternative to the rapid-acting insulin analogavailable.Objecti...

Introduction: Medullary thyroid carcinoma (MTC) and papillary thyroid carcinoma (PTC) are two distinct neoplasms originating from follicular and parafolicular-C cells, respectively. These pathologies have always been considered different from each other in terms of their incidence, their cell origin and their histopathological features. Concurrent occurrence of MTC and PTC in the same patient is an unusual event and its occurrence as true mixed medullary-follicular-derived car...

Introduction: About 50% of patients with medullary thyroid carcinoma (MTC) have persistent or recurrent disease after surgery.For a calcitonin (ct) value greater than 150 pg/ml, it is suggested by international guidelines performing additional imaging exams (AIE) for evaluating the presence of distant metastasis. It is often difficult to assess the presence of nodal disease and secondary liver lesions (often miliary) by ‘morphological’ imaging ...

Introduction and objectives: Multiple surgeries are associated with many complications in the local recurrence of papillary thyroid carcinoma. Our objective is to evaluate the efficiency of the enolization in the recurrent metastatic cervical lymph nodes in patients with limited nodal disease.Material and methods: We studied 13 patients (six males and seven females) with a mean age of 43±14.4 years with papillary thyroid carcinoma intervened (total ...

Case of 33 years old male patient with an unremarkable past medical history, who after a car accident, a cystic nodular right neck mass was incidentally found by MRI of cervical spine. Physical examination revealed a mildly tender right neck mass. He was clinically and biochemically euthyroid. Denied history of neck irradiation. No family history of thyroid disease or thyroid cancer. Excisional biopsy of right neck mass showed metastasic well differentiated papillary carcinoma...

51 y/o female with past medical history of migraine headache, brought to UR because of hypoactivity, generalized weakness, confusion, lack of balance and dysarthria since one day of evolution. No medications. No Habits. Past history: negative for hypertension, cardiac disease or dyslipidemia. Physical examination: normal vital signs and weight. Alert, awake, and oriented only in person. Palpable nontender left thyroid lobe. Bilateral hyperreflexia.Labs: ...